Low-density microarray analysis of TGFβ1-dependent cell cycle regulation in human breast adenocarcinoma MCF7 cell line
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Effects of berberine on proliferation, cell cycle distribution and apoptosis of human breast cancer T47D and MCF7 cell lines
Objective(s):Berberine, a naturally occurring isoquinoline alkaloid, has shown antitumor properties in some in vitro systems. But the effect of berberine on breast cancer has not yet been completely studied. In this study, we evaluated anticancer properties of berberine in comparison to doxorubicin. Materials and Methods: The antiproliferative effects of berberine and doxorubicin alone and in ...
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Introduction: Hormesis and adaptive responses are two important biological effects of low-dose ionizing radiation (LDIR) in organism and mammalian cell lines. Notably, LDIR generates distinct biological effects in cancer cells from normal cells, e.g., it may affect the growth of cancer cells via the activation of certain cell signaling pathway, which does not exist in normal ...
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Background and Objective: Garlic has been known worldwide as a dietary constituent with many pharmacological effects. The present in vitro study was designed to investigate the putative anticancer effect of garlic extract on cancer cells, and if this effect was through apoptosis induction. Material and Methods: Human colon adenocarcinoma cells HT29 were treated with different doses (1, 5 a...
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Objective(s):Multidrug resistance (MDR) of cancer cells is a major obstacle to successful chemotherapy. Overexpression of breast cancer resistance protein (BCRP) is one of the major causes of MDR. In addition, it has been shown that PI3K/Akt signaling pathway involves in drug resistance. Therefore, we evaluated the effects of novel approaches including siRNA directed against BCRP and targeted t...
متن کاملeffects of berberine on proliferation, cell cycle distribution and apoptosis of human breast cancer t47d and mcf7 cell lines
objective(s):berberine, a naturally occurring isoquinoline alkaloid, has shown antitumor properties in some in vitro systems. but the effect of berberine on breast cancer has not yet been completely studied. in this study, we evaluated anticancer properties of berberine in comparison to doxorubicin. materials and methods: the antiproliferative effects of berberine and doxorubicin alone and in c...
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ژورنال
عنوان ژورنال: Biopolymers and Cell
سال: 2014
ISSN: 0233-7657,1993-6842
DOI: 10.7124/bc.000888